Recently Published

New published work or pre-prints by the lab.

• 2026
  The immunology behind inflammaging – causes, sources, and mechanismsReview

  Sturmlechner I^*, LeBrasseur NK, Weyand CM, Goronzy JJ^*. ^*co-corresponding authors

  Journal of Allergy and Clinical Immunology (JACI), 2026

Key Publications

Selected work by Dr. Sturmlechner. For a complete list, see Dr. Sturmlechner's Google Scholar.

• 2026
  Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity

  Sturmlechner I^†*, Jain A^†, Jiang J, Okuyama H, Mu Y, Own M, Weyand CM, Goronzy JJ^*. ^†co-first authors. ^*co-corresponding authors

  Science Advances, 2026
• 2025
  Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells

  Sturmlechner I^†*, Jain A^†, Jiang J, Hu B, Jadhav RR, Cao W, Okuyama H, Tian L, Weyand CM, Goronzy JJ^*. ^†co-first authors. ^*co-corresponding authors

  Nature Communications, 2025
• 2023
  T cell fate decisions during memory cell generation with agingReview

  Sturmlechner I^†, Jain A^†, Mu Y, Weyand CM, Goronzy JJ. ^†co-first authors.

  Seminars in Immunology, 2023
• 2023
  TRIB2 safeguards naive T cell homeostasis during aging

  Cao W^†*, Sturmlechner I^†, Zhang H, Jin J, Hu B, Jadhav RR, Fang F, Weyand CM, Goronzy JJ^*. ^†co-first authors. ^*co-corresponding authors

  Cell Reports, 2023
• 2022
  Senescent cells limit p53 activity via multiple mechanisms to remain viable

  Sturmlechner I, Sine CC, Jeganathan KB, Zhang C, Fierro Velasco RO, Baker DJ, Li H, van Deursen JM

  Nature Communications, 2022
• 2021
  p21 produces a bioactive secretome that places stressed cells under immunosurveillance

  Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM

  Science, 2021